Early Diagnosis of Neonatal Sepsis

In an article presented by the Journal of Pediatric Infectious Diseases, the abstract of the article states that sepsis is one of the most significant contributors to mortality and morbidity in the neonatal population. The need to find specific biomarkers that provide meaningful information about the diagnosis of sepsis in neonatals is ongoing. The article calls out the study aimed to investigate the utility of N-terminal pro b-type natriuretic peptide (NT-proBNP) as a diagnostic biomarker in newborn infants with late-onset sepsis. This marker is associated with blood volume and pressure and with the work that the heart must do in pumping blood throughout the body. The marker is primarily used to help detect, diagnose and evaluate the severity of heart failure. BNP is a hormone produced by the heart. Levels go up when heart failure develops or gets worse, and levels go down when the heart failure is stable. The marker of cardiac dysfunction is associated with sepsis in preterm neonates.

The increased levels of B-type natriuretic peptide (BNP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) are related with the dysfunction of a cardiovascular system and systemic inflammation.

In the study that was done, it included 87 patients diagnosed with sepsis and 35 controlled patients. The median NT-proBNP were higher in septic patients showing a significant correlation in measuring white blood cell count, serum C-reactive proteins (CRP), plasma interleukin and whole blood levels.

In conclusion, plasma NT-proBNP levels were higher in septic neonates.

If you or someone you know or love has been injured or died in labor, or as defined as a maternal death, Kreisman Law Offices is prepared to handle your case. Robert Kreisman of Kreisman Law Offices has more than 40 years of experience and has been successfully handling maternal death cases.

Kreisman Law Offices has prevailed in trials and settlements in Chicago, Illinois and its surrounding areas and successful resolved cases for birth injury lawsuits, wrongful death claims and maternal death cases for these many years.

With our years of experience in trying and settling birth trauma injury cases, maternal death cases and wrongful death matters, Kreisman Law Offices provides the best possible services to our clients and have achieved unsurpassed results. Our service is unmatched. Please call us 24 hours a day at 312-346-0045 or toll free 800-583-8002 for a free and immediate consultation or complete a contact form online on our website.

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